Frailty

Frailty is a clinical state of increased vulnerability due to age-associated decline in physiological reserve, resulting in compromised ability to cope with external everyday or acute stressors. (1) Preoperative frailty is associated with increased postoperative complications, mortality, and longer-term negative outcomes, including falls, lower quality of life, non-home discharge, and prolonged length of stay. (2,3)

Screening Tools

The FRAIL scale has been validated as a preoperative screening tool for frailty and as a predictor of mortality and postoperative complication. (4) Many geriatricians find ADLs and IADLs as a useful adjunct to a screening tool.

Prehabilitation and Optimization Algorithm

Prehabilitation and Optimization Recommendations

Patient Education	Refer to online patient resources for frailty-specific physical prehab and nutrition resources, including information on how to access physiotherapy for patients with frailty
Preoperative Risk Discussion	Assess goals of care and advance care plan (e.g., complete MOST form) Identify substitute decision maker Assess for cognitive impairment and ability to provide consent for surgery Refer to online provider resources for assessment tools (e.g., Mini-Cog or MMSE)
Referral for Comprehensive Geriatric Assessment (CGA)	Referral to geriatrician can be useful prior to moderate/highly invasive surgery If no local specialist, refer to provider online resources for telehealth consultation options

References

1. Fried, L. P., Tangen, C. M., Walston, J., Newman, A. B., Hirsch, C., Gottdiener, J., Seeman, T., Tracy, R., Kop, W. J., Burke, G., McBurnie, M. A., & Cardiovascular Health Study Collaborative Research Group (2001). Frailty in older adults: evidence for a phenotype. The journals of gerontology. Series A, Biological sciences and medical sciences, 56(3), M146–M156. https://doi.org/10.1093/gerona/56.3.m146

2. Lin, H. S., Watts, J. N., Peel, N. M., & Hubbard, R. E. (2016). Frailty and post-operative outcomes in older surgical patients: a systematic review. BMC geriatrics, 16(1), 157. https://doi.org/10.1186/s12877-016-0329-8

3. McIsaac, D. I., Aucoin, S. D., Bryson, G. L., Hamilton, G. M., & Lalu, M. M. (2021). Complications as a Mediator of the Perioperative Frailty–Mortality Association. Anesthesiology, 134(4), 577–587. https://doi.org/10.1097/ALN.0000000000003699

4. Gong, S., Qian, D., Riazi, S., Chung, F., Englesakis, M., Li, Q., Huszti, E., & Wong, J. (2023). Association Between the FRAIL Scale and Postoperative Complications in Older Surgical Patients: A Systematic Review and Meta-Analysis. Anesthesia and analgesia, 136(2), 251–261. https://doi.org/10.1213/ANE.0000000000006272